Sepsis-associated jaundice

Nuclear jaundice in neonatal (umbilical) sepsis with jaundice.

It is a well-known fact that after familial jaundice in the new-born there not rarely remain certain cerebral symptoms which are related to a particular localization of the icteric staining in the brain substance, especially in the basal ganglia. The first description of icterus gravis neonatorum was given by Orthl', and the familial character was stressed by Schmorl2. In recent years a number ...

Jaundice associated with naproxen.

Hepatic injury in association with naproxen therapy is described and documented by liver biopsy in one patient. Histological findings were consistent with a drug-induced hepatitis, and cessation of therapy led to reversal of the clinical and biochemical changes. Circumstantial evidence is in favour of a hypersensitivity response to the drug rather than direct hepatotoxicity. Increased awareness...

On the cause of nuclear jaundice in neonatal sepsis with jaundice.

Neonatal Jaundice Associated with Familial

It is now well established that hyperbilirubinaemia and even kernikterus may occur in the newborn in association with glucose 6 phosphate dehydrogenase (G6PD) deficiency, in the absence of any of the other causes of neonatal jaundice (Panizon, 1960a, b; Doxiadis, Fessas, and Valaes, 1960; Doxiadis, Fessas, Valaes, and Mastrokalos, 1961; Fessas, Doxiadis, and Valaes, 1962; Smith and Vella, 1960;...

Jaundice-associated acute kidney injury

After spontaneous vaginal delivery, a 32-week-gestation female baby presented immediately with respiratory distress, APGAR scores 0 (1 min) and 2 (5 min), generalized skin oedema and bilateral pleural effusion. The prenatal history was unremarkable. The clinical diagnosis was nonimmune hydrops fetalis, and treatment with mechanical ventilation, surfactant, prostaglandin and supportive measures ...